Suggested Level of Knowlege: Detailed
LOs
BT_PM 1.9 Describe the pharmacology of the following agents applicable to pain management, including:
· Opioids
· Tramadol
· Local anaesthetic agents (also refer to the Regional and local anaesthesia clinical fundamental)
· NSAIDs
· Paracetamol
· NMDA antagonists
· Anticonvulsants
· Antidepressants
· Corticosteroids
· Inhalational analgesics – nitrous oxide, methoxyflurane
BT_RA 1.3 Discuss the pharmacology of local anaesthetic agents including:
· Mechanisms of action
· Comparative pharmacology of different agents
· Toxicity
· Use of adjuvant agents to enhance the quality or extend duration of block
· Pharmacokinetics of drugs administered in the epidural and subarachnoid space
Past SAQs
2005.2 Write brief notes on the physico-chemical properties of lidocaine (lignocaine).
2004.2 Write a brief description of the pharmacology of ropivacaine.
2004.1, 2000.1 Briefly describe the factors that determine skin penetration by local anaesthetics. Briefly describe the forumulation and pharmacology of EMLA® cream.
2001.2 Describe the required pharmacological characteristics of local anaesthetic formulations intended for topical use.
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