Rolapitant (By mouth)
roe-LA-pi-tant
Prevents nausea and vomiting caused by chemotherapy.
Drug classes
Antiemetic (About this – PubMed Health)
Uses
Uses of This Medicine
Rolapitant is used together with other medicines to prevent delayed nausea and vomiting that is caused by cancer medicines (chemotherapy). Rolapitant is a substance P/neurokinin 1 (NK1) receptor antagonist. It works by blocking the signals to the brain that cause nausea and vomiting.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Tablet
Your doctor will tell you how much medicine to use. Do not use more than directed. On the first day of your chemotherapy session, take this medicine 1 to 2 hours before treatment. Do not take this medicine more than once every 14 days.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Do not use this medicine if you are also taking thioridazine.
Some medicines can affect how rolapitant works. Tell your doctor if you are using dextromethorphan, digoxin, irinotecan, methotrexate, pimozide, rifampin, rosuvastatin, or topotecan.
When Not To Use
This medicine is generally considered safe for most people. Talk to your doctor if you have concerns.
Warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Fever, chills, cough, sore throat, body aches
If you notice these less serious side effects, talk with your doctor:
Dizziness
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Varubi
There may be other brand names for this medicine.