Transcribed by BingDing

Part 10 of 1st one, THE THYROID East West Healing Blog Talk Radio 2011

Whosits:

So, while we’re on the topic, and I don’t want to go to much into ???preface???, but, let’s go and chat about estrogen levels, and we talk about how they block hypothyrodism but how hypothyroidism can raise those, and I think, you know she was concerned because most, well I shouldn’t say most, but a lot of women are being prescribed these medications, number one, most people are having issues with detoxifying their body of these estrogens, number two, and having this unopposed estrogen in the body leads to specific dysfunctions or diseases like clotting or edema, fybrosis, cysts and all these things.

Ray Peat:

There are very close interactions between the increased estrogen and you mentioned clotting, and estrogen increases seratonin dominance and seratonin and estrogen both promote and are promoted by the polyunsaturated fats and the low thyroid condition so it forms sort of a polar cluster with the energizing thyroid and uh the good nutrients, sugar, minerals, protein and so on, maintaining and energizing the structure, the emergency stress things, the prostaglandins, seratonin, histamine, cortisol and estrogen are all on the short term defensive side but when they become dominant they deform the proper regulatory systems.

There’s a special problem with the basis for diagnosing estrogen deficiency because in the absence of anti-estrogen substances such as progesterone the estrogen in the blood can go to a very low level because the estrogen is staying inside cells, and progesterone knocks it out of cells, inactivates it, but causes it to appear in the blood stream on its way out the kidneys, so in the absence of progesterone doctors will measure a low level of serum estrogen and prescribe it even though under that situation it’s very likely that their tissues, breast and uterus in particular, are actually overloaded with a chronic supply of estrogen.

Whosits:

Ha, I wish I could summarize that. I’m going to move on, I highly recommend everyone relistening to these shows over and over again because it’s an hour plus of information you could literally sit down and make probably fiftly pages of notes on. I want to talk about CO2, carbon dioxide, in the thyroid because I know you’re a fan of CO2 but for many ??? ??? of your stuff you talk about the thyroid and you talk about carbon dioxide, how do thyroid hormones raise CO2 and what are the advantages of having higher CO2 levels.

Ray Peat:

That means that you’re oxidizing things completely, getting, uh, if you oxidise fats completely you get rid of any toxic effect from the free fatty acids, but you also stop producing lactic acid and stop that whole route of inflammatory, harmful processes, free fatty acids and lactic acid, but the carbon dioxide itself binds to all of our proteins, for example hemoglobin. In the diabetic they look at the amount of sugar, or fragments, attached to protein such as hemoglobin, but it’s actually the breakdown of fatty acids which contribute about 95% of these ???glycon??? proteins that accumulate in diabetes and aging, but when we are producing enough carbon dioxide it not only protects the cell by removing the excitatory calcium but it also binds to all of our proteins that have a lysine group or another amine group exposed and these amines are where the breakdown products, free radicals, fatty acids, and so-called glycation end products, ??? ???, it’s where they bind, so carbon dioxide binds protectively to proteins keeping them in the native, youthful state which happens to be, uh the things called hormone receptors are in a different state when there is adequate carbon dioxide, insulin is in a different state, growth hormone, all of our peptide hormones, can bind carbon dioxide, becoming a different substance, so all of our hormone system is deranged if we just hyperventilate and blow out too much carbon dioxide or if we’re hypothyroid basically we’re in effect hyperventilating even at rest, producing lactic acid instead of carbon dioxide.